Chromosome 10 & 11

CHROMOSOME 10 :

• RET protoncogene
• MEN 2

Note : 

MEN 1 - Chromosome 11

MEN 2 - Chromosome 10

CHROMOSOME 11 :

• Sickle cell dis.
• Wilms tumour 
• Ataxia telangiectasia
• Beta thallesemia
• MEN 1
• Human insulin gene.
• PTH gene
• Niemann pick disease (Type A & B )
• Folate Receptor genes

Note:
Alpha thallesemia - Chromosome 16
Beta thallesmia - Chromosome 11

Folate Receptor genes (FOLR 1 adult , FOLR 2 fetal , FOLR 3 ) are mapped on Chromosome 11
Reduced folate carrier (SLC19A1) (Folate Transporter) - Chromosome 21.



Human Insulin gene - Chromosome 11
Insulin Receptor gene - Chromosome 19

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