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Contact Factor deficiency without bleeding




Contact Factor deficiency without bleeding :

Includes deficiency of
  • Factor XII
  • Prekallikrein

  • High-molecular-weight kininogen

With severe deficiency (contact factor activity less than 1% of normal ) , there is marked increase in aPTT.
This results in a Paradoxical situation showing marked increase aPTT with NO bleeding.

Note : Here No treatment is required even if Major surgery is to be Undertaken.





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