0 Local Anaesthetic Drugs - Important points

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Procaine :

• 1-2% for nerve block
• Metabolized by Pseudocholinesterase
• LA of choice in Malignant Hyperthermia

Chloroprocaine :

• Shortest acting
• High pKa but still Fast acting (this is an exception)
• Most acidic of all LA
• Contraindicated for spinal anaesthesia

Lignocaine

• 5% - heavy - spinal
• 4% - Surface
• 2% - Jelly for uretheral
• 1-2% - Extradural
• 1% - Nerve block
• 0.5% - IVRA
• Maximum safe dose : 3mg/kg ,( if with adrenaline - 7mg/kg)

Bupivacaine :

• Long acting
• Dose : 2mg/kg (max. safe dose) , ( if with adrenalin - 3mg/kg.)
• Never IV

Prilocaine : 

• S/E - Methemoglobenemia (T/t - Methylene blue)

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