Cytomegalovirus (CMV)
- Periventricular Calcifications
- Chorioretinitis
- Convulsions
Asymptomatic CMV is leading cause of Sensoryneural hearing loss ( 7% cases of CMV infection )
Diagnosis :
CMV is in all body secretions
Thus can be isolated - Urine and Saliva are best specimens for CMV culture
Antigen PP65 - PCR against this is used.
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| Typical "owl eye" inclusion indicating CMV infection of a lung pneumocyte |
Treatment :
IV - Gancyclovir (Side effect - Bone marrow depression)
if resistant - Foscarnet
Image Source : http://en.wikipedia.org/wiki/File:Cytomegalovirus_01.jpg
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