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Acute flaccid paralysis



Acute flaccid paralysis (AFP)

Age group : 0 - < 15 years

Provided pseudoparalysis is ruled out :
  1. Scurvy
  2. Osteomyelitis
  3. Syphilis
  4. Hypokalemia

Causes of AFP :

1. Paralytic poliomyelitis
  • Asymmetrical 
  • at onset of paralysis - high grade fever

2. Traumatic neuritis  : History of IM gluteal

3. Transverse myelitis : (Usually viral) Varicella

4. Guillain-BarrĂ© Syndrome - GBS (AIDP) 
  • follows C.Jejuni diarrhoea - 10 days later - GBS
    other - Mycoplasma
  • Ascending , Areflexic , Symmetrical paralysis
  • Proximal muscles affected 1st
  • CSF : Albumino-cytological dissociation (at the end of 2nd week) - MCQ
  • NCV : decreased , symmetrical demyelinating neuropathy
  • Treatment : Iv-Ig , Plasmapheresis



MedicoNotebook - Founder : DrShiviMudgal , Co-Founder : DrAyushGoel

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